Pediatric Research | Stony Brook Children's

Advancing Children's Medicine Through Research

Stony Brook Children's not only provides advanced pediatric care, it also advances the practice of pediatric medicine. Our pioneering research — carried in world-class research facilities under the direction of expert faculty — includes drug and device development, genetic studies, and extensive access to clinical trials, including international multi-site studies.

We are the only continuously NIH-funded pediatric and obstetric site providing HIV/AIDS clinical trials in Suffolk County since 1992. We also are carrying out groundbreaking studies on the best treatments for children with kidney disease, cystic fibrosis, and inborn errors of metabolism, as well as studies on the development of literacy. Our neonatologists have an extensive research program devoted to understanding fetal lung development. Some of the research currently being conducted at Stony Brook that may change the shape of children's medicine includes:

Development of new therapies for inborn errors of metabolism
Non-invasive ventilation techniques
Use of rhIGF-1 for the treatment of cystic fibrosis in infants
Studying the prevalence of Celiac Disease in children and adolescents with autoimmune thyroid disease
Integration of neural stimuli to regulate gene expression in the nervous system
Developmental and functional outcomes in children who have a positive newborn screen for Krabbe Disease, a rare inherited neurologic disorder affecting the central and peripheral nervous systems
Studying the potential role of thiazolidinediones in beta cell function, which might benefit children with newly diagnosed Type I diabetes
Studying the effect of weight loss, exercise, and healthy lifestyle on childhood asthma in a pediatric obesity group
Using a novel instrument to study the effect of glycemic control on prospective memory, with implications for children and adolescents with Type I diabetes
Looking at the impact on academic success of literacy skill development for children at risk
Examining neuropsychiatric manifestations of gluten intolerance in children with Celiac Disease
Genotype-Phenotype correlation in Phenylketonuria
Looking at Hyperoxia and inflammatory mediators; hyperoxia is a common neonatal condition
Differentiation of GERD from Eosinophilic esophagitis

These and other studies are funded by the National Institutes of Health (NIH), the Centers for Disease Control (CDC), and other granting agencies. The results of these investigations have been published in numerous peer reviewed journals.